BioportTriComboUK patient and professional information

Glucosamine injection for the hip

With chondroitin and hyaluronic acid, in one pre-filled syringe.

Illustration of the hip joint from the front, with a needle placed into the joint space between the ball of the femur and its socket

In short

  • Indicated for synovial joints, which include the hip.1
  • Studied in the knee.3
  • Three ingredients, one pre-filled syringe, one injection per treatment.2
  • Whether it is an option for you is decided by the clinician who examines your hip.

The hip

The hip is a ball and socket. The rounded head of the thigh bone sits in a cup in the pelvis, and both surfaces are covered in cartilage and bathed in joint fluid.

In osteoarthritis that cartilage thins and the fluid loses some of its cushioning quality. The joint becomes stiff and painful, often felt in the groin or the front of the thigh rather than the side of the hip.

How it tends to show

  • Groin or front-of-thigh pain when walking, on stairs or getting out of a car.
  • Stiffness first thing in the morning, or after sitting, that eases with movement.
  • Trouble reaching your foot to put on socks or shoes.
  • Pain that wakes you at night or stops you lying on that side.

Application

The hip joint is deep, so clinicians usually place the needle with ultrasound or X-ray guidance. One pre-filled syringe is injected into the joint space. The manufacturer describes two treatment cycles a year, six months apart.2

Bioport TriCombo pack and pre-filled syringe

Research

TriCombo’s published clinical study is in the knee: a 2025 single-centre study of Kombihylan, the combination the manufacturer names as TriCombo’s active principles, which measured the properties of the joint fluid six weeks after injection.3,2

The knee study, for professionals

Other joints

Studies mentioned on this page

  1. 1.Nikovari Bio Tech Oy. Bioport TriCombo instructions for use. Supplied with each pack, 2025. View source
  2. 2.Nikovari Bio Tech Oy. Bioport TriCombo product brochure. Manufacturer document, 8 pages, 2025. View source
  3. 3.Iordan DA, Coman MG, Hrisca-Eva OD, Stavrică-George A, Gherghin AC, Onu I. Enhanced Synovial Fluid Rheology in Moderate Knee Osteoarthritis Through Combined Intra-Articular Hyaluronic Acid and Multimodal Physiotherapy: A Monocentric Observational Study. Journal of Clinical Medicine, 14(17):6051, 2025. View DOI

Talk to a clinic

This website gives information, not clinical advice. Only a clinician who has examined your hip can say whether TriCombo is an option for you.

Where to have itFAQ